Iatrogenic Creutzfeldt-Jakob Disease from Commercial Cadaveric Human Growth Hormone

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منابع مشابه

Iatrogenic Creutzfeldt-Jakob Disease from Commercial Cadaveric Human Growth Hormone

unvaccinated dogs and in the endangered Simien jackal (Canis simensis) of Ethiopia. Journal of Veterinary Medicine Series B. 1992;39:233–5. http://dx.doi. org/10.1111/j.1439-0450.1992.tb01162.x 7. Zhang YZ, Fu ZF, Wang DM, Zhou JZ, Wang ZX, Lv TF, et al. Investigation of the role of healthy dogs as potential carriers of rabies virus. Vector Borne Zoonotic Dis. 2008;8:313–20. http://dx.doi. org/...

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Iatrogenic Creutzfeldt-Jakob disease following human growth hormone therapy: case report.

We report the case of a 41-year-old man with iatrogenic Creutzfeldt-Jakob disease (CJD) acquired after the use of growth hormone (GH) obtained from a number of pituitary glands sourced from autopsy material. The incubation period of the disease (from the midpoint of treatment to the onset of clinical symptoms) was rather long (28 years). Besides the remarkable cerebellar and mental signs, the p...

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Human growth hormone-related iatrogenic Creutzfeldt-Jakob disease with abnormal imaging.

BACKGROUND Although more than 160 cases of iatrogenic Creutzfeldt-Jakob disease (iCJD) from human growth hormone (hGH) treatment have been documented, to our knowledge abnormal cerebellar findings on magnetic resonance imaging (MRI) have not been reported. OBJECTIVE To report a case of hGH-related iCJD with abnormal cerebellar MRI findings on fluid-attenuated inversion recovery (FLAIR) and di...

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Iatrogenic Creutzfeldt-Jakob Disease, Final Assessment

The era of iatrogenic Creutzfeldt-Jakob disease (CJD) has nearly closed; only occasional cases with exceptionally long incubation periods are still appearing. The principal sources of these outbreaks are contaminated growth hormone (226 cases) and dura mater grafts (228 cases) derived from human cadavers with undiagnosed CJD infections; a small number of additional cases are caused by neurosurg...

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Iatrogenic transmission of Creutzfeldt-Jakob disease.

Creutzfeldt-Jakob disease is a rare progressive neurological disorder which is eventually fatal. Attention has recently been focused upon the iatrogenic transmission of this disease by four published reports of patients developing Creutzfeldt-Jakob disease associated with the administration of human growth hormone preparations originally prepared from human cadaver pituitaries. Characterized cl...

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ژورنال

عنوان ژورنال: Emerging Infectious Diseases

سال: 2013

ISSN: 1080-6040,1080-6059

DOI: 10.3201/eid1904.121504